Cefetamet Pivoxil is indicated for the treatment of infections caused by sensitive microorganisms and in particular- Otolaryngeal infections: Otitis media, Sinusitis, Tonsillo-pharyngitis Infections of the lower respiratory tract: Tracheo-bronchitis, Bronchitis, Pneumonia Infections of the complicated and uncomplicated urinary tract: Acute pyelonephritis, Acute gonorrhea, Urethritis.
Third generation Cephalosporins
Adults and children over 12 years: 500 mg twice daily. Children under 12 years: Usual dosage is 10 mg/kg twice daily. 16-30 kg (approximately 3-9 years): 250 mg twice daily 31-40 kg (approximately 9-12 years): 375 mg twice daily >40 kg (approximately over 12 years): 500 mg twice daily Uncomplicated gonorrhea, acute urethritis, uncomplicated cystitis: Single dose of 1500-2000 mg. For better absorption Cefetamet Pivoxil should be taken one hour before or after a meal.
Cefetamet is contraindicated in patients with hypersensitivity to Cefetamet, any other cephalosporin or penicillins or any other ingredient of this formulation. Cefetamet should be administered with caution to the patients who have previously manifested allergy phenomena or gastrointestinal problems. An anaphylactic reaction demands an emergency treatment. Like with other antibiotics, Cefetamet can cause the opportunistic development of non-sensitive germs (Candida, Enterococci, and difficult Clostridium); in such cases, a suitable therapy should be given. Discontinuation of the antibiotic helps to restore the normal microflora and the internal functions. In presence of difficult Clostridium cases, the treatment of choice is Vancomycin for oral use and the inhibiting drug of the peristalsis are contraindicated.
Most common gastrointestinal side effects may include diarrhea, nausea & vomiting. Like with other wider spectrum antibiotics, in the course of treatment with Cefetamet internal colonization from difficult Clostridium can be observed. In some cases, this microorganism or its toxin has been identified
The main preclinical studies carried out with Cefetamet have not evidenced teratogenic effects. There are no available data regarding safe use of Cefetamet during pregnancy & lactation. Therefore, it should be used during pregnancy & lactation only if the potential benefit justifies the potential risk to the fetus.
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