It is used to kill bacteria responsible for infections which can occur in your blood, bones or joints. This antibiotic is generally used when the bacteria causing the infection are not satisfactorily eliminated by other antibiotics (eg penicillin) or when patients may be allergic to other antibiotics. Your doctor, however, may prescribe it for another purpose.
Miscellaneous Antibiotics
Teicoplanin is a glycopeptide-antibiotic produced by Actinoplanes teichomyceticus. It is presented as a sterile, pyrogen-free ivory white powder for reconstitution with water for injection. It is freely soluble in water and on reconstitution gives a clear solution. Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. Peptidoglycan synthesis is blocked by specific binding to D-alanyl-D-alanine residues.
How much will be given? On the first day of treatment most patients generally receive TWO doses of it, 12 hours apart. During the following days, most patients receive ONE dose each day. After the first day, the daily dose varies between 6 mg and 12 mg for each kilogram of body weight, depending on the type of infection. An adult of normal weight (around 70 kg) would therefore receive a single daily dose of between 400 mg and 800 mg. Patients with kidney problems may need lower doses (or doses less often) than other patients. Your doctor can calculate how much it you require if you have kidney problems. How it is given? it injection should be prepared and administered by a qualified health professional (doctor, pharmacist or nurse). The vial of it powder should be mixed carefully with the sterile water, which is included in the pack, to form a clear solution. The solution may be injected into a vein directly over about 5 minutes, or it may be mixed with other sterile solutions and delivered into a vein from a 'drip' bottle or bag over about 30 minutes. it solution may also be injected directly into a muscle. How long it will be given If you have an infection in your blood, you will probably need to receive a daily injection of it for 2 to 4 weeks. If you have an infection in any bones or joints, you may require a daily injection of it for 3 to 6 weeks
Due to potential for increased adverse effects, Teicoplanin should be administered with caution in patients receiving concurrent nephrotoxic or ototoxic drugs, such as Aminoglycosides, Amphotericin B, Cyclosporion and Frusemide.
is contraindicated in patients who have exhibited previous hypersensitivity to Teicoplanin
local pain and redness at the injection site ? rash ? dizziness ? nausea ? headache ? stiffness ? fever ? vomiting ? diarrhoea ? balance problems ? ringing in the ears ? problems hearing
here are no adequate and well-controlled studies in pregnant women about administration of Teicoplanin; this drug should be used during pregnancy only if clearly needed. Information about the excretion of Teicoplanin in milk is not known
Store at a temperature not exceeding 30°C in a dry place. Protect from light. The reconstituted solution should be used immediately, or stored under refrigeration (2 to 8° C) for 24 hours maximum.
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