Levonorgestrel is an emergency contraceptive that can be used to prevent pregnancy following unprotected intercourse or a known or suspected contraceptive failure.
Progestogen; Contraceptive
Oral contraceptives containing levonorgestrel suppress gonadotropins, inhibiting ovulation. Specifically, levonorgestrel binds to progesterone and androgen receptors and slows the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. This process results in the suppression of the normal physiological luteinizing hormone (LH) surge that precedes ovulation. It inhibits the rupture of follicles and viable egg release from the ovaries. Levonorgestrel has been proven to be more effective when administered before ovulation.
Levonorgestrel tablet should be taken orally as soon as possible within 72 hours after unprotected intercourse.
Interactions with other medicines and other forms of interaction: Simultaneous administration of certain anticonvulsant agents (phenobarbitone, phenytoin, primidone, carbamazepine), also other medications such as rifampicin, and griseofulvin can reduce or suppress the effectiveness of this emergency contraception.
Levonorgestrel should not be given to pregnant women. Levonorgestrel, like progestin-only contraceptives, does not protect against HIV infection (AIDS) & other sexually transmitted diseases.
Nausea/vomiting, abdominal pain, tiredness, dizziness, changes in vaginal bleeding, breast tenderness, diarrhea, or headache may occur. Tell your doctor immediately.
It should not be given to pregnant women & it will not interrupt the pregnancy. Levonorgestrel is secreted into breast milk. The potential exposure of an infant to levonorgestrel can be reduced if the breastfeeding woman takes the tablets immediately after feeding & avoids nursing following each tablet administration.
No acute toxicity has been demonstrated with this medicine in the case of intake of several doses. The efficacy of this medicine is not guaranteed if the dose has been omitted.
Do not exceed the expiry date printed on the outer packaging. Keep the tablet in the outer carton. Keep the medicine away from children. Store in cool dry conditions (below 30° C).
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