Acute hemorrhoidal attacks, Chronic hemorrhoidal disease, organic & functional chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs, pain, nocturnal cramps.
Diosmin and Hesperidin is a phlebotonic drug and a vascular protecting agent. It reinforces venous tone by prolonging the activity of parietal noradrenaline. Thus Diosmin and Hesperidin decreases venous capacitance, venous distensibility, and venous emptying time.
Diosmin and Hesperidin protects the microcirculation by fighting the microcirculation damaging process; It combats venous inflammation by decreasing leukocyte activation, and as a consequence, by inhibiting the release of inflammatory mediators, principally free radicals and prostaglandin. Thus Diosmin and Hesperidin normalizes capillary permeability and strengthens capillary resistance.
Diosmin and Hesperidin acts on the lymphatic system, It improves lymphatic drainage by increasing lymph flow and lymph oncotic pressure.
Acute hemorrhoidal attacks: 3 tablets twice daily for 4 days, then 2 tablets twice daily for three days & if required then 1 tablet twice daily. Chronic hemorrhoids : 1 tablet twice daily, Chronic venous insufficiency : 1 tablet twice daily initially for seven days. Duration may be increased depending on severity.
No evidence of drug incompatibility (drug interaction) has been reported in clinical trials.
Chronic venous insufficiency and its complications should be diagnosed and management monitored by a physician. It is contraindicated for anyone having a hypersensitivity to any ingredient in the product.
Gastric disorder & neurovegetative disorders (feeling of discomfort).
Experimental studies in animal have not demonstrated any teratogenic effects & no harmful effect have been reported in women to date. Breast feeding is not recommended during treatment.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Each film coated tablet contains-
Diosmin micronised BP 450 mg
Hesperidin micronised INN 50 mg
Each DS film coated tablet contains-
Diosmin micronised BP 900 mg
Hesperidin micronised USP 100 mg
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