Duodenal ulcer, Gastric ulcer, Gastrooesophageal reflux disease.
Famotidine is a histamine H2-receptor antagonist. Famotidine completely inhibits the action of histamine on H2- receptors of parietal cell. It inhibits basal, overnight and pentagastrin stimulated gastric acid secretion. The H2- receptor antagonist activity of Famotidine is slowly reversible, since the drug dissociates slowly from H2-receptor.
20 mg twice daily or 40 mg at night. Maintenance therapy as Famotack 20 one tablet at night.
No clinically important drug interactions have been identified. Famotidine does not interact with the cytochrome P450-linked drug-metabolizing enzyme system.
Headache, dizziness, constipation & diarrhoea, nausea and/or vomiting, abdominal discomfort or distention, anorexia, fatigue, rash.
Should be prescribed only if clearly needed. It is best avoided by nursing mothers.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.