Cefdinir is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, Infections
Third generation Cephalosporins
Cefdinir is a semisynthetic third generation oral cephalosporin antibotic. It has a broad spectrum bactericidal activity against a wide range of common pathogens, including b-lactamase producing strains like Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella pneumoniae, and Proteus mirabilis. As with other cephalosporins, bactericidal activity of Cefexta results from inhibition of cell wall synthesis.
Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days. Child: -6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.
Antacids: Cefdinir should be taken at least 2 hours interval of antacid administration.
Iron supplement: Cefdinir should be taken at least 2 hours interval of iron supplement administration.
Probencid: It inhibits the renal excretion of cefdinir.
Cefdinir is contraindicated in patients with known allergy to the cephalosporin class of antibiotics. Cefdinir, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Cefdinir should be reduced.
Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Following administration of single 600 mg doses, Cefdinir was not detected in human breast milk.
Store at room temperature and protect from light. After reconstitution the suspension can be used within 7 days if kept at room temperature and within 14 days if kept in refrigerator (2-8°C). Always keep the bottle tightly closed.
.png&w=384&q=75)