It is a vaccine that provides protection against a serious infectious disease called yellow fever. Yellow fever occurs in certain areas of the world and is spread to man through the bites of infected mosquitoes. It is given to people who: - are travelling to, passing through or living in an area where yellow fever occurs, - are travelling to any country that requires an International Certificate of Vaccination for entry (this may depend on the countries previously visited during the same trip), - may handle infectious materials such as laboratory workers. To obtain a valid vaccination certificate against yellow fever, it is necessary to be vaccinated in an approved vaccination centre so that an International Certificate of Vaccination can be issued. This certificate is valid from 10 days after the first dose of vaccine. When a booster is needed, the certificate (see Section 3) is valid immediately after the injection.
Vaccines, Anti-sera & Immunoglobulin
Live, attenuated virus stimulates active immunity to Yellow fever; conveys active immunity via stimulation of production of endogenously produced antibodies. Yellow fever vaccine is used for active immunisation against yellow fever. Each dose (usually 0.5 ml) contains at least 1000 mouse LD50 units.
Dosage It is given as a single, 0.5 millilitre dose to adults and children from 6 months of age. The first dose should be given at least 10 days before protection from yellow fever is needed. This is because it takes 10 days for the first dose of vaccine to work and provide good protection against the yellow fever virus. The protection provided by this dose is expected to last at least 10 years and may be life-long. A booster with one dose (0.5 millilitre) may be needed: - if you or your child had an insufficient response to the first dose, - or after at least 10 years if it is required as a condition of entry in some countries. How it is given It is given as an injection by a doctor or nurse. It is usually injected just underneath the skin but it can be given into a muscle. It must not be injected into a blood vessel. child In some cases, more than the recommended dose was used. In these cases, when side effects were reported, the information was in line with what is described in Section 4. If you have any further questions on the use of this vaccine, ask your doctor, pharmacist or nurse.
Tell your healthcare professional if you are taking, have recently taken or might take any other medicines. If you have recently had any treatment or medicine which may have weakened your immune system, the vaccination must be delayed until your laboratory results show that your immune system has recovered. Your doctor will advise you when it is safe for you to be vaccinated. Yellow Fever Vaccine can be given at the same time as measles vaccine or vaccines against typhoid fever (those containing the Vi capsular polysaccharide) and/or hepatitis A. Vaccination with Yellow Fever Vaccine may lead to false positive results of blood tests for dengue or Japanese encephalitis. If you or your child have in the future such tests prescribed, please inform your doctor about this vaccination.
are allergic to: - the active substance, or - any of the other ingredients of this vaccine (listed in Section 6), or - eggs or chicken proteins. - have experienced a severe allergic reaction after a previous dose of any yellow fever vaccine, - is less than 6 months old, - have a poor or weakened immune system for any reason, such as illness or medical treatments (for example corticoids or chemotherapy), - have a weakened immune system due to HIV infection. Your doctor will advise you if you can still receive it based on the results of your blood tests, - are infected with HIV and have active symptoms due to the infection, - have a history of problems with your thymus gland or have had your thymus gland removed for any reason, - have an illness with a high or moderate temperature or an acute illness. The vaccination will be postponed until you have recovered.
Rash, itching or hives on the skin - Swelling of the face, lips, tongue or other parts of the body - Difficulty swallowing or breathing - Loss of consciousness - High fever with headache and confusion - Extreme tiredness - Stiff neck - Inflammation of brain and nerve tissuesHeadache ? Mild or moderate tiredness or weakness (asthenia) ? Pain or discomfort at the injection site ? Muscle pains ? Fever (in children) ? Vomiting (in children)
If you are pregnant, or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before being vaccinated. You should not receive it unless this cannot be avoided. Your doctor or pharmacist can advise you on whether it is essential that you are vaccinated while pregnant or breastfeeding.
Keep out of the sight and reach of children. Do not use this vaccine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month. Store in a refrigerator (2°C-8°C). Do not freeze.
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