It is indicated in water and sodium depletion. It provides Dextrose as a nutrient in a suitable medium of Sodium Chloride or it may also be employed as a source of Sodium Chloride. It is usually used in the maintenance and replacement of fluid, electrolyte and carbohydrate in patients (especially for neonates & infants) who are unable to take fluid and nutrients by mouth e.g. in case of persistent vomiting, during and after surgery, shock or accidents.
Standard Electrolytes Solution
Dextrose and Sodium Chloride Injection, USP has value as a source of
water, electrolytes, and calories. It is capable of inducing diuresis
depending on the clinical condition of the patient.
The volume and rate of infusion of the solution depends on the clinical condition, age and body surface area of the patient and judgment of the physicians.
Caution must be exercised in the administration of Dextrose and Sodium Chloride Injection, USP to patients receiving corticosteroids or corticotropin. Studies have not been conducted to evaluate additional drug/drug or drug/food interactions with Dextrose and Sodium Chloride Injection, USP.
These solutions are contraindicated where the administration of sodium or chloride could be clinically detrimental. Serum electrolyte concentration should be carefully monitored. Sodium Chloride should be administered with caution to patients with congestive heart failure, peripheral or pulmonary oedema, impaired renal function or pre-eclampsia.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
FDA pregnancy category C. It is not known whether dextrose 5% in water will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether dextrose 5% in water passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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