Dextrose + Sodium Chloride solution is indicated in Dehydration accompanied by small Sodium Chloride deficiency. It provides Dextrose as a nutrient in a suitable medium of Sodium Chloride. It is usually used in the maintenance and replacement of fluid, electrolyte and carbohydrate in patients who are unable to take fluid and nutrients by mouth e.g. in pre and post operative fluid regime, shock or accidents.
Intravenous fluid preparations
This is a sterile solution of Dextrose and Sodium Chloride in water for injection. Each 100 ml of solution contains Dextrose Monohydrate equivalent to Dextrose Anhydrous B.P. 5.0 gm and Sodium Chloride B.P. 0.9 gm. This represents 5% Dextrose in isotonic Sodium Chloride solution. The approximate concentration of sodium and chloride ions in Dextrose is 150 mmol/lit.
Dose is variable. Generally 60-120 drops/minutes are given intravenously or according to physician$#$#$#$s recommendation. Dose depends on the clinical condition, age and body surface area of the patients.
Hypersensitivity. As the preparation contains Sodium Chloride, it should be administered with caution to patients with congestive heart failure, peripheral or pulmonary oedema, impaired renal function or pre-eclampsia. Serum glucose concentration should also be carefully monitored and concurrent use of insulin may be needed in case of diabetic patients. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy , contains particles, or after expiry date.
Febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
Pregnancy Category - C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.