Fenticonazole Nitrate is indicated in: Genital candidiasis (vulvovaginitis, colpitis, infectious fuor) Trichomonasis Vaginal infections sustained by mixed forms of Trichomonas vaginalis and Candida albicans.
Topical Antifungal preparations
Fenticonazole is a broad-spectrum antimycotic agent with activity against dermatophytes and yeasts. Fenticonazole has also been shown to exhibit antibacterial action, with a spectrum of activity that includes bacteria commonly associated with vaginal infections and antiparasitic action against the protozoan Trichomonas vaginalis. Therefore, Fenticonazole may be an ideal topical alternative to multi-agent treatment of mixed infections involving mycotic, bacterial, dermatophyte and/or Trichomonas spp.
Vaginal tablet- Vaginal infections: Fenticonazole 600 mg vaginal tablet (followed by a second administration 24 hours later, if necessary). Candida albicans infections: Fenticonazole 600 mg vaginal tablet administration in the evening. Should the symptoms persist, a second administration may be repeated after three days. The vaginal tablet must be introduced deep into the vagina and pushed well up to the fornix. To avoid re-infection, it is recommended that the partner undergoes concurrent treatment with Fenticonazole Cream or similar Azole Cream. Cream: Apply 2% cream once daily
Not investigated. Since systemic absorption of Fenticonazole after application is low, interactions with other drugs are unlikely.
Contraindicated in case of hypersensitivity to Fenticonazole and other Imidazoles. Discontinue if sensitization or irritation occur. Pregnancy and lactation.
After intravaginal administration slight transient burning (which usually disappears rapidly) may occasionally happen. Prolonged topical application may cause sensitisation reactions. Fenticonazole is generally well tolerated by the mucous membranes; only exceptionally mild and transient erythematous reactions have been reported. After topical application or intravaginal administration, a slight burning sensation may occur, usually subsiding soon. Should more persistent irritation occur or resistant micro-organism develop, suspend the treatment and seek the doctor's advice. Due to poor absorption of Fenticonazole, no systemic efects should occur, provided the above instructions are carefully observed.
It is not recommended in pregnancy. Safety in breastfeeding has not been established.
Because of the low systemic absorption after vaginal application, overdosage is unlikely.
Protect from light & moisture. Keep below 30° C temperature, protected from light & moisture. Do not freeze. Keep out of the reach of children.
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