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Docosanol cream is indicated for the topical treatment of acute and recurrent oral-facial Herpes simplex episodes (Herpes labialis or cold sores or fever blisters).
Docosanol exerts its antiviral effect on HSV by inhibiting fusion of the virus envelope with host cell plasma membranes, resulting in inhibition of viral entry into cells and subsequent viral replication.
Adults and Children of 12 years of age and older: Apply 5 times a day until healed. Treatment should be begun at earliest signs or symptoms of herpes infection (Blisters, open sores, pain in the infected area, itching, burning, tingling or numbness).
Hypersensitivity to Docosanol or any other components of the formulation.
Generally Docosanol is well tolerated. Rarely burning, dryness of skin, itching, rash, swelling & headache are seen after administration of Docosanol.
Pregnancy: There are no adequate and well-controlled studies in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies using rats or rabbits.
Nursing Mothers: It is not known whether Docosanol is excreted in breast milk. Because many drugs are excreted in breast milk, consideration should be given to discontinue nursing temporarily or withhold the drug while the mother is nursing.
No instance of accidental ingestion of Docosanol has been reported. If ingested, gastric lavage and general supportive measures should be employed.
Docosanol 10%