Dithranol & combined preparations
Dithranol: Dithranol can block the supply of ATP to epidermal cells of the skin, thereby cutting off the energy supply to Keratinocytes. This mechanism may at least partially explain the curative effect of dithranol on psoriasis. It has antifungal properties. Salicylic acid: It is a Keratolytic agent. Salicylic acid accelerates desquamation, thereby eliminating the invading fungus and helping the medication penetrate the skin. Keratolysis is the process of shedding the hard layer of the epidermis. Salicylic acid completes the desquamation process by dissolving the intercellular cement, which holds the scales of the stratum corneum together. Salicylic acid works primarily by increasing the shedding of the scales.
Boric acid: It has the ability to inhibit the growth of bacteria and fungi (bacteriostatic and fungistatic properties).
Apply on the skin 2 times daily.
If you use other drugs or over the counter products at the same time, the effects of this ointment may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. this ointment may interact with the following drugs and products:
Fluocinolone
Hydroquinone
Isotretinoin
None reported
Riboflavin
Tretinoin
Hypersensitivity, acute & pustular psoriasis
burning sensation & irritation, stains skin, hair and fabrics
DA has not yet classified the drug into a specified pregnancy category.
Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children.
Per 100 grams of ointment contains-
Dithranol BP 0.75 grams
Boric Acid BP 1.75 grams
Salicylic Acid BP 2.50 grams
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