Chlorhexidine is effective against gingivitis and periodontitis and probably also against caries and bad breath. The use of chlorhexidine lavages for the prevention of oral infections due to immunodeficiency is documented as well.
Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.
MOUTH/THROAT Oral hygiene;Gingivitis: Adult: Rinse mouth w/ 10 ml of a 0.2% soln for 1 min bid-tid.
Advice of healthcare professional should be sought if using or have recently used any other drugs. Hypochlorite bleaches may cause brown stains to develop in fabrics which have previously been in contact with preparations containing Chlorhexidine.
Brain, meninges, middle ear or sensitive tissues. Avoid contact w/ eyes except when dilute solutions are used.
Skin sensitivity; irritation of conjunctiva, mucosal irritation; reversible brown staining of the teeth; tongue discoloration; parotid gland swelling.
It is not known if chlorhexidine passes from mother to fetus during pregnancy. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Use of chlorhexidine oral rinse by a nursing mother is unlikely to adversely affect her infant.
Keep in a cool and dry place protected from light. Shake the bottle well before use.