Histalex is indicated in urticaria,pruritus of various sites,eczema,drug rash,allergic dermatitis,hay fever,vasomotor rhinitis,allergic asthma etc.
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.
Age : Tablet 1-5 years ? tablet 2-3 times daily 5-12 years ?-1 tablet 2-3 times daily Above 12 years 1-2 tablet 2-3 times daily Age: Syrup 1-5 years 1 teaspoonful 2-3 times daily 5-12 years 1-2 teaspoonful 2-3 times daily Above 12 years 2-4 teaspoonful 2-3 times daily
Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone.
There is no specific contraindication for Chlorpheniramine Maleate Chlorpheniramine may cause drowsiness,sedation. Patients should not drive or operate machinery during administration of Chlorpheniramine. It should be used with caution in epilepsy,glaucoma,hepatic diseases and prostatic hypertrophy.
Drowsiness,sedation,dizziness,muscular weakness and gastrointestinal upset
Pregnancy Category B. Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.
Store in a cool (Below 25°C temperature) and dry place protected from light. Keep out of the reach of children.
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