Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
Celiprolol is a vasoactive beta-1 selective adrenoceptor antagonist with partial beta-2 agonist activity. The beta-2 agonist activity is thought to account for its mild vasodilating properties. It lowers blood pressure in hypertensive patients at rest and on exercise. The effects on heart rate and cardiac output are dependent on the pre-existing background level of sympathetic tone. Under conditions of stress such as exercise, celiprolol attenuates chronotropic and inotropic responses to sympathetic stimulation. However, at rest minimal impairment of cardiac function is seen.
Adult: 200-400 mg once daily.
Hypersensitivity, sinus bradycardia, >1st degree heart block, cardiogenic shock, uncompensated heart failure, hypotensive patients. Pregnancy (2nd & 3rd trimesters).Asthma. Lactation
Nausea, abdominal discomfort, diarrhoea; CHF, AV nodal block & bradycardia, palpitations; headache, fatigue, dizziness, insomnia; Raynaud’s phenomenon; orthostatic hypotension; bronchial obstruction; tremor, rash, muscle cramps; impotence.
Talk to your doctor before taking this medicine if you are pregnant, might become pregnant, or think you may be pregnant. If your doctor cannot find a safer alternative you may be given Celectol. If you take Celectol during pregnancy, particularly in the last 3 months, you should tell your midwife. This is because your baby may be affected when it is born. Any effects usually begin on the first day after birth and can include lower than normal levels of glucose in the blood (hypoglycaemia), slow heart beat, heart failure or having trouble breathing. If your baby has any of these side effects when it is born and you are worried, tell your doctor or midwife. You should not breast-feed if you are taking Celectol. This is because small amounts may pass into the mothers milk. If you are breast-feeding or planning to breast-feed, talk to your doctor or pharmacist before taking this medicine. Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or breast-feeding.
You may have symptoms such as slow heart beats, low blood pressure, feeling dizzy or weak, difficulty in breathing, wheezing or heart problems. Contact your doctor or go to the nearest hospital causalty department immediately. Take this leaflet or some tablets with you so your doctor will know what you have taken.
Keep container in the outer carton. Do not store above 25°C. Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
.png&w=384&q=75)