CalcIum Carbonate 250 mg or 500 mg: ThIs Is used for the treatment or preventIon of calcIum depletIon In patIents In whom dIetary measures are Inadequate. CondItIons that may be assocIated wIth calcIum defIcIency Include hypoparathyroIdIsm, achlorhydrIa, chronIc dIarrhea, vItamIn D defIcIency, steatorrhea, sprue, pregnancy and lactatIon, menopause, pancreatItIs, renal faIlure, alkalosIs, and hyperphosphataemIa. CalcIum Carbonate Is beIng used IncreasIngly often to treat hyperphosphataemIa In chronIc renal faIlure as well as those on contInuous ambulatory perItoneal dIalysIs (CAPD) and haemodIalysIs. Many patIents are unable to tolerate suffIcIent doses for complete phosphate control and requIre addItIonal measures such as strIngent dIetary phosphate restrIctIon or relatIvely small doses of alumInIum hydroxIde. CalcIum Carbonate contaInIng preparatIons can provIde short-term relIef of dyspeptIc systems but are no longer recommended for long-term treatment of peptIc ulceratIon. CalcIum Carbonate 1000 mg: ThIs Is IndIcated for the management of condItIons assocIated wIth hyperIdIty and for fast relIef of acId IndIgestIon, heartburn, sour stomach and upset stomach.
Specific mineral preparations
This is a preparation of Ascorbic Acid (Vitamin C). Ascorbic Acid is an essential nutrient, which means it cannot be produced by the body and therefore must be obtained from diet or supplements. Ascorbic Acid has many important functions. It is required for tissue growth & repair, Adrenal gland function, enhanced immunity & healthy gums. As an antioxidant, it gives protection against harmful pollution, infection & reduces cellular damage. As a coenzyme, it is a necessary factor for wound healing, drug metabolism & metabolism of cholesterol & folic acid. As an essential nutrient, vitamin C supports healthy hair & skin, strengthens the immune system and maintain overall good health.
Calcium Carbonate is always used orally and when used as an antacid the recommended doses for adults are equivalent to 540-2000 mg Calcium Carbonate per day, doses for children being half of those for adults. As a dietary supplement, such as for the prevention of osteoporosis, 1250-3750 mg Calcium Carbonate (500-1500 mg calcium) daily is recommended in general, but again this will need to be tailored to the individual patient depending on any specific disease such as Calcium deficiency, malabsorption or parathyroid function. In pregnancy and lactation the recommended daily dose of calcium is 1200-1500 mg. In chronic renal failure the doses used vary from 2.5 - 9.0 gm Calcium Carbonate per day and need to be adjusted according to the individual patient. To maximize effective phosphate binding in this context the Calcium Carbonate should be given with meals
Potentially hazardous interactions: Ascorbic acid is incompatible in solution with aminophylline, bleomycin, erythromycin, lactobionate, nafcillin, nitrofurantoin sodium, conjugated oestrogen, sodium bicarbonate, sulphafurazole diethanolamine, chloramphenicol sodium succinate, chlorthiazide sodium and hydrocortisone sodium succinate.
Useful interactions: Ascorbic acid increases the apparent half-life of paracetamol and enhances iron absorption from the gastrointestinal tract.
Hypersensitivity to the Calcium Carbonate or any inactive ingredient of the medication. Hypercalcemia (e.g. in hyperparathyroidism, overdosage of vitamin D, demineralizing tumours such as plasmacytomas and bone metastases), severe hypercalcuria, several renal insufficiency.
irritating to the GI tractconstipation. Hypercalcaemia
Calcium containing drugs are used widely in pregnancy by way of oral calcium supplementation. Calcium Carbonate can be used in lactating women too.
Should be stored in a dry place below 30˚C.
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