Infantile beriberi : Loss of appetite,vomiting,greenish stools,followed by paroxysmal attacks of muscular rigidity. Adult beriberi : Dry skin,discomfort,confabulation followed by paralysis. Wernicke's encephalopathy : Neuropsychiatric disorder may develop in some cases due to alcohol intake. Korsakoff's syndrome : Diabetes,cancer and in other cases for example the patients having nutritional intake parenterally where Vitamin B1 is absent may arise Vitamin B1 deficiency. Fatigue,anorexia Gastrointestinal disturbance Neurological disorder Other Vitamin B1 deficiency in case of pregnancy and lactation.
Thiamine Hydrochloride (Vitamin B1) is an essential constituent for the metabolism of carbohydrate and a lot of amino acids. Utilization of pyruvic acid and amino acid in tissue are decreased in Thiamine deficiency. So pyruvic acid and lactic acid are accumulated and cause Beri-beri. In adult, approximately 1 mg of Thiamine per day is completely degraded by the tissues, and this is roughly the minimal daily requirement. Thiamine is well absorbed from the Gastro-intestinal tract and is widely distributed to most body tissues. Excess of the body requirements are excreted in the urine as unchanged or as metabolites.
DOSAGE AND ADMINISTRATION Mild to moderate chronic deficiency : ? tablet daily. Severe deficiency : 2-3 tablets daily.
Neurovit has no known severe interactions with other drugs.
A-B1 is contraindicated in patients who are hypersensitive to it
No known side effect have yet been established.
The drug may be given safely to neonates,children,pregnant and lactating women and elderly patients.
Neurovit overdose doesn't cause toxicity.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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