Hyoscine butylbromide is an antispasmodic medicine which is taken to relieve cramps in the stomach, intestines or bladder. In particular, it helps to ease bloating and the spasm-type pain that can be associated with irritable bowel syndrome and diverticular disease. It works by relaxing some of the muscles in your gastrointestinal and urinary systems. Hyoscine butylbromide is available on prescription. You can also buy it from a pharmacy, without a prescription, to relieve the symptoms of irritable bowel syndrome, providing your symptoms have previously been diagnosed by a doctor. There is also a medicine called hyoscine which is taken to prevent travel sickness. There is more information about this in a separate medicine leaflet called Hyoscine for travel sickness.
Anticholinergic; Antispasmodic Agent
Hyoscine butylbromide is an antispasmodic agent which relaxes the smooth muscle of the gastrointestinal, biliary and urinary tracts. It is believed to act predominantly at the parasympathetic ganglia in the walls of the viscera of these organs. Structurally, hyoscine exists as a quaternary ammonium compound and as a single positively charged cation throughout the entire pH range.
Tablets: The usual dose of Hyoscine tablets is 10 to 20 mg tablets per day. If you need to take this medication regularly, then the usual dose is 10 mg tablet 3 to 5 times a day. The maximum dose is 6 tablets per day. Injection: The usual dose of Hyoscine Injection is 10 mg to 20 mg given by intramuscular (into a muscle), intravenous (into a vein), or subcutaneous (under the skin) injection. The maximum daily dose is 100 mg. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here,do not change the way that you are using the medication without consulting your doctor. Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
As hyoscine butylbromide can reduce the motility and secretory activity of the gastrointestinal system, the systemic absorption and pharmacologic effects of other oral medications may be delayed.
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking hyoscine butylbromide it is important that your doctor or pharmacist knows: If you are pregnant or breast-feeding. If you have prostate problems. If you have any other digestive system problems, such as reflux disease, diarrhoea, ulcerative colitis, or severe constipation. If you have high blood pressure, or if you have recently had a heart attack. If you have glaucoma. This is a condition where the pressure in your eyes is raised. If you have been told by a doctor that you have a fast heart rate. If you have Down's syndrome. If you are less than 12 years old or over 65 years old. If you have been told you have nerve damage, a condition called autonomic neuropathy. If you have a condition that causes muscle weakness, called myasthenia gravis. If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. If you have ever had an allergic reaction to a medicine.
Hyoscine butylbromide side-effects (these affect less than 1 in 100 people) are Dry mouth, Dry skin, sweating, Itchy skin rash
This medicine is not usually recommended for use during pregnancy as its safety has not been established. It should only be used if the expected benefit to the mother is greater than any possible risks to the developing baby, particularly in the first trimester. Seek medical advice from your doctor. It is not known if this medicine passes into breast milk, although only small amounts are likely to be found due to the properties of the medicine. The class of medicines that this one belongs to may reduce the production of breast milk. The manufacturer states that this medicine is not recommended for use during breastfeeding. Get advice from your doctor before taking this medicine if you are breastfeeding.
Single oral doses of up to 590 mg and quantities of active drug up to 1090 mg within 5 hours have produced dry mouth, tachycardia, slight drowsiness and transient visual disorders. Other symptoms include urinary retention, reddening of the skin, and inhibition of gastrointestinal motility. Other symptoms which occurred in animals and which may be encountered in humans include: shock, Cheyne-Stokes respiration, respiratory paralysis, clonic spasms, paresis of the striated muscle, coma, paralytic ileus and cystoparalysis.
Store in a cool and dry place, protected from light and moisture. Keep out of the reach of the children.
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