For the dIsInfectIon of clean and Intact skIn. For pre-operatIve surgIcal hand dIsInfectIon, hand dIsInfectIon on the ward prIor to aseptIc procedures or after handlIng contamInated materIals. For dIsInfectIon of the patIents’ skIn prIor to surgery or other InvasIve procedure
At physiologic pH, chlorhexidine salts dissociate and release the positively charged chlorhexidine cation. The bactericidal effect is a result of the binding of this cationic molecule to negatively charged bacterial cell walls. At low concentrations of chlorhexidine, this results in a bacteriostatic effect; at high concentrations, membrane disruption results in cell death.
Adults- Pre-operative surgical hand disinfection: Dispense 5 ml of solution and spread thoroughly over both hands and forearms, rubbing vigorously. When dry apply a further 5 ml and repeat the procedure. Antiseptic hand disinfection on the ward: Dispense 3 ml of solution and spread thoroughly over the hands and wrists rubbing vigorously until dry. Disinfection of patients skin: Prior to surgery apply the solution to a sterile swab and rub vigorously over the operation site for a minimum of 2 minutes. Chlorhexidine Gluconate is also used for preparation of the skin prior to invasive procedures such as venepuncture. Elderly and children: There are no specialdosing regimes for children and the elderly.
Chlorhexidine is incompatible with soaps and other anionic agents. Hypochlorite bleaches may cause brown stains to develop in fabrics which have previously been in contact with chlorhexidine solutions.
Chlorhexidine Gluconate is contraindicated for persons who have previously shown a hypersensitivity reaction to chlorhexidine. However, such reactions are extremely rare
Irritative skin reactions can occasionally occur.Allergic reacttion may occur.
No untoward effects are known
Keep away from eye, head and meninges & middle ear. Store in a cool and dry place, away from light, Keep out of the reach of children.
This preparation contains-
0.5% w/v Chlorhexidine Gluconate (equivalent to 2.5% v/v Chlorhexidine Gluconate solution BP)
70% v/v Isopropyl Alcohol BP