It is used to prevent or treat low blood Calcium levels in people who do not get enough Calcium from their diets. It may be used to treat conditions caused by low Calcium levels such as ? Bone loss (Osteoporosis) ? Weak bones (Osteomalacia/Rickets) ? Decreased activity of the parathyroid gland (Hypoparathyroidism) ? Certain muscle disease (Latent tetany) ? Hip joint plastic surgery To ensure adequate Calcium, it may also be used in certain conditions such as ? Pregnancy and lactation ? Premenstrual syndrome (PMS) ? Post-menopausal osteoporosis ? Senile osteoporosis ? Drug (Phenytoin, Phenobarbital, or Prednisone) induced osteoporosis
This contains Calcium Orotate, a calcium supplement with a functional amino acid chelating ligand- orotic acid. Orotic acid assists the transport of calcium through cellular membrane structures, thus facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Furthermore, Orotate is involved in the synthesis of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) of the various calcium supplements on the market, Calcium Orotate gets high marks because of the compound's ability to penetrate complex cell membranes so that it can be metabolized in cartilage.
Calcium Orotate 400 mg: As an addition to the daily diet, 2-3 tablets are usually recommended with meal, after meal or as directed by physician. Calcium Orotate 740 mg: As an addition to the daily diet, 1-2 tablets are usually recommended with meal, after meal or as directed by physician.
Calcium can decrease absorption of the following drugs when taken together: biphosphonates (e.g., alendronate), quinolone antibiotics (e.g., ciprofloxacin, levofloxacin), and tetracycline antibiotics (e.g., doxycycline, minocycline), levothyroxine, phenytoin (an anticonvulsant), and tiludronate disodium (to treat Paget's disease). Thiazide-type diuretics can interact with Calcium supplements, increasing the risks of hypercalcemia and hypercalciuria. Both aluminum- and magnesium-containing antacids increase urinary calcium excretion. Mineral oil and stimulant laxatives decrease calcium absorption. Glucocorticoids, such as prednisone, can cause calcium depletion and eventually osteoporosis when they are used for months. Oral contraceptives as well as estrogen compounds reduce calcium. Anti-inflammatories such as NSAIDs, Aspirin, Ibuprofen deplete calcium. Corticosteroids deplete calcium.
Contraindicated in patients with known hypersensitivity to Calcium Orotate or to any component of the formulation. Calcium Orotate is also contraindicated in conditions like incomplete or infrequent bowel movements, kidney stone, kidney disease, sarcoidosis, increased activity of the parathyroid gland, high amount of Calcium in urine, high amount of Calcium in the blood, extreme loss of body water. Precaution is needed in patients with kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, a certain lung disease (sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome).
Common side effects are bloating and swelling in the abdomen. Constipation, nausea, vomiting, headache, increased thirst/urination and intense abdominal pain may occur.
Women who are pregnant and breast-feeding need more Calcium. Pregnancy related high blood pressure is a common and serious risk for women and their babies, taking supplemental forms of Calcium Orotate can help reduce this risk.
Keep out of the reach of children. Keep in a cool & dry place. Protect from light.
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