It is used to treat knee pain in patients with osteoarthritis who have not received relief from other treatments. It is injected into the joint capsule, to act as both a shock absorber and a lubricant for the joint.
Sodium salt of hyaluronic acid
Sodium Hyaluronate is a viscous solution consisting of a high molecular weight fraction of purified natural sodium hyaluronate in buffered physiological sodium phosphate. It has a pH of 6.8-7.5. Hyaluronic acid is an important component of the body's extracellular matrix and is present in a particularly high concentration in cartilage and synovial fluid. Endogenous hyaluronic acid provides viscosity and elasticity to synovial fluid, which is fundamental for its lubricating and shock absorbing properties. It is essential for the correct structure of proteoglycans in articular cartilage. In osteoarthritis there is an insufficient amount and a change in the quality of hyaluronic acid in synovial fluid and cartilage. The intra-articular administration of hyaluronic acid into arthritic joints improves joint functions.
Dry eye conditions TO THE EYE Adult: Apply as required
Sodium Hyaluronate should not be intra-articularly administered simultaneously or mixed with other products. It should not be used concomitantly with disinfectants containing quaternary ammonium salts because hyaluronic acid can precipitate in their presence
Sodium hyaluronate is contraindicated in people who are sensitive to hyaluronate preparations, or when there are infections or skin disease at the injection site.
warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected; nausea, stomach pain; trouble walking; swelling in your hands or feet; back pain, joint pain, muscle pain; numbness or tingly feeling; headache, dizziness; or runny or stuffy nose, sneezing, sore throat.
Sodium hyaluronate has not been formally assigned to a pregnancy category by the FDA. Animal studies have failed to reveal evidence of fertility impairment or teratogenicity. There are no controlled data in human pregnancy. Sodium hyaluronate is only recommended for use during pregnancy if benefit outweighs risk. There are no data on the excretion of sodium hyaluronate into human milk.
Hyronate injection should be stored in a cool (below 25° C) and dry place and protected from light. Protect from freezing.
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