Prophylaxis & treatment of allergic rhinitis
Following topical administration into the nasal mucosa, Fluticasone propionate produces anti-inflammatory and vasoconstrictor effects. The exact mechanism of these actions remains unknown but may involve a reduction in the following: number of mediator cells (basophil, leukocytes and mast cells) at the epithelial level, number of eosinophils, the sensitivity of sensory nerves to mechanical stimuli, secretory response to cholinergic receptor stimulation, and fibroblast activity. Other mechanisms may involve - inhibition of capillary dilation and permeability, stabilization of lysosomal membranes and subsequent prevention of release of proteolytic enzymes.
Adults: 02 sprays in each nostril once daily, preferably in the morning. Children (4 to 11years of age) 01 spray in each nostril once daily
Hypersensitivity to any of its components. Care must be taken while transferring patients from systemic steroid to Fluticasone nasal spray if there is any reason to suppose that their adrenal function is impaired.
Nasal irritation & stinging. Nasal septum perforation, dryness of nose & throat, unpleasant taste & smell & epistaxis reported rarely.
There are no adequate and well-controlled studies in pregnant women. Fluticasone Propionate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Fluticasone Propionate is excreted in human breast milk. Because other corticosteroids are excreted in human milk, caution should be exercised when Fluticasone Propionate nasal spray is administered to a nursing woman.
Keep all medicines out of reach of the children. Store in a cool and dry place protected from light.
50 mcg/Spray, 93 mcg/Spray
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