Treatment or prevention of bronchospasm in adults, adolescents, & children 6 years of age & older with reversible obstructive airway disease.
Levosalbutamol is a single isomer beta 2-agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. Levosalbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamol. Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects.
Tablets: Adults & adolescents above 12 years: 1-2 mg three times daily, Children (upto 11 years): 1 mg three times daily. Syrup: Adults: 5-10 ml three times daily, Children (upto 11 years): 5 ml three times daily.
Other short acting sympathomimetic bronchodilators or epinephrine should be used with caution with Levosalbutamol. If additional adrenergic drugs are to be administered by any route, they will be used with caution to avoid deleterious cardiovascular effects.
Hypersensitivity to any of the components of the formulation. Potentially serious hypokalemia may result from ?2 agonist therapy. Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia & by concomitant treatment with xanthine derivatives, steroids & diuretics. Oral Levosalbutamol should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias or hypertension.
Hypokalaemia, palpitation, fine tremors of the skeletal muscle (particularly the hand), muscle cramps, nausea, vomiting, burning substernal or epigastric pain, diarrhoea, nervousness, headache, dizziness, fatigue & sleeplessness.
Use of oral Levosalbutamol in pregnant or nursing mothers should be considered only if the expected benefit to the mother is greater than any possible risk to the foetus or the infant.
The expected symptoms with over dosage are those of excessive beta-adrenergic stimulation and the symptoms listed under side effects. In the event of serious poisoning, the stomach should be emptied and, if necessary, a beta-blocker administered with caution in patients with a history of bronchospasm.
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.
.png&w=384&q=75)