Used for cataracts, asthma, respiratory infections, skin disorders, aging skin, sunburns, cystic fibrosis, infertility, impotence, chronic fatigue syndrome (CFS), peptic ulcers, for certain inherited diseases and to prevent allergies.
Vitamin E acts as an antioxidant in the body. Vitamin E protects polyunsaturated fatty acids (which are components of cellular membrane) and other oxygen-sensitive substances such as vitamin A & vitamin C from oxidation. In premature neonates irritability, edema, thrombosis and hemolytic anemia may be caused due to vitamin E deficiency. Creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival or increased in vitro hemolysis by oxidizing agents have been identified in adults and children with low serum tocopherol concentrations.
ORAL Vitamin E deficiency: Adult: 40-50 mg of d-- tocopherol daily. Child: Neonate: 10 mg/ kg once daily; 1 mth-18 yr: 2-10 mg/kg/day, up to 20 mg/kg. Supplementation in cystic fibrosis: Adult: 100-200 mg daily of dl-- tocoferil acetate or 67-135 mg daily of d-- tocopherol. Child: As --tocopheryl acetate: 1 mth-1 yr 50 mg once daily; 1-12 yr 100 mg once daily; 12-18 yr 200 mg once daily. Dose to be adjusted as needed. Abetalipoproteinaemia: Adult: 50-100 mg/kg daily of dl---tocoferil acetate or about 33-67 mg/kg daily of d---tocopherol. Child: Neonate: 100 mg/kg once daily; 1 mth-1 B yr: 50-100 mg/kg once daily.
Vitamin E may impair the absorption of Vitamin A & function of Vitamin K and potentiates the effect of Warfarin.
Some research suggests that taking large amounts of a multivitamin plus a separate vitamin E supplement might actually increase the chance of developing prostate cancer in some men. High doses can also cause nausea, diarrhea, stomach cramps, fatigue, weakness, headache, blurred vision, rash, and bruising and bleeding.
Hypertension; myopathy; thrombophloebitis; fatigue, weakness, nausea, headache, dizziness, blurred vision, flatulence, diarrhoea, abdominal pain. Topical: Contact dermatitis.
When used in the recommended daily amount, vitamin E is POSSIBLY SAFE for pregnant women. There has been some concern that taking vitamin E supplements might be harmful to the fetus when taken in early pregnancy. However, it is too soon to know if this is an important concern. Vitamin E is excreted into human milk. Adverse effects of the nursing infant are unknown. Maternal supplementation is recommended only if the diet does not provide sufficient vitamin E to meet the recommended dietary allowance (RDA) during lactation.
Transient gastrointestinal disturbances have been reported with doses greater than 1000 IU daily and where necessary, general supportive measure should be employed.
Keep in a dry place away from light and heat. Keep out of the reach of children.
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