Mefenamic acid is used for the short-term treatment of mild to moderate pain from various conditions. It is also used to decrease pain and blood loss from menstrual periods. Mefenamic acid is known as a nonsteroidal anti-inflammatory drug (NSAID).
Mefenamic acid contains Mefenamic Acid which is a nonsteroidal agent with demonstrated analgesic, anti-inflammatory and antipyretic activity due to its dual action on prostaglandins. It inhibits the enzymes of prostaglandin synthetase and also antagonizes the actions of prostaglandin at the receptor sites.
ORAL Rheumatoid arthritis; Mild to moderate pain; Dental pain; Postoperative pain; Dysmenorrhoea; Osteoarthritis; Menorrhagia: Adult: 250-500 mg tid. Child: >6 mth: 25 mg/kg daily in divided doses for up to 7 days.
Aspirin: As other NSAIDs, concomitant administration of Mefenamic Acid and Aspirin is not generally recommended because of the potential of increased adverse effects.
Warfarin: Mefenamic Acid can inhibit platelet aggregation and may prolong the prothrombin time in patients on warfarin therapy
Inflammatory bowel disease; peptic ulcer; neonates: pregnancy (3rd trimester), lactation. Coronary artery bypass graft surgery, severe renal impairment, severe heart failure. Renal & hepatic impairment, asthma. Monitor blood counts & liver function during long-term therapy. Drowsiness may affect ability to perform skilled tasks. Elderly.
Abdominal pain, dyspepsia, constipation, diarrhoea, nausea, GI ulcers; oedema; bronchospasm; headache, drowsiness, insomnia, visual disturbances; CHF, hypertension, tachycardia, syncope; urticaria, rash; thrombocytopenia, aplastic anaemia, agranulocytosis; tinnitus; elevated liver enzymes; abnormal renal function. Autoimmune haemolytic anaemia; convulsions (overdosage).
During early pregnancy, use mefenamic acid only if prescribed. Mefenamic acid is not recommended during the third trimester of pregnancy as it may harm a fetus. Mefenamic acid passes into breast milk and is not recommended for use while breastfeeding.
Keep away from light, store in a cool and dry place. Keep out of reach of children.
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