Bisacodyl is a diphenolic compound. Its chemical structure is similar to that of phenolphthalein. It is widely used as a laxative. Bisacodyl acts on the colon to stimulate peristalsis and on the small bowel and colon to increase intraluminal water and electrolytes. When applied to the caecum, Bisacodyl initiates a response in the entire colon.
ORAL Constipation: Adult: 5-10mg at night. Child: >4 yr: 5 mg at night time. Bowel evacuation: Adult: Initially, 10- 20 mg the night before the procedure followed by 10 mg supp admin rectally the next morning. Child: >10 yr: Same as adult dose. 4-10 yr: 5mg the night before the procedure & 5mg supp admin rectally the following morning. RECTAL Constipation: Adult: 10 mg suppository/enema admin in the morning. Child: <10 yr: 5mg in the morning.
Acute surgical abdomen or intestinal obstruction, severe dehydration, faecal impaction, chronic use. Swallow the tab whole. Pregnancy; inflammatory bowel disease.
Abdominal discomfort (colic, cramps>. Suppositories may cause irritation & proctitis.
Bisacodyl should only be given during pregnancy when need has been clearly established. Bisacodyl tablets or suppositories have been used during human pregnancy without evidence of uterine relaxation. Due to the minimal absorption of bisacodyl, fetal risk is considered low. These are safer laxatives to take during pregnancy and while breastfeeding.
Store in a cool and dry place, protected from light.
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