Irritable bowel syndrome, Infantile colic, GIT spasm, Diverticulitis, Abdominal colic, Diarrhoea, Dysentery.
Anticholinergic; Antispasmodic Agent
Dicycloverine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract. Dicycloverine HCl Injection is a sterile, pyrogen-free, aqueous solution for intramuscular injection (Not For Intravenous Use). It works at specific receptors, called cholinergic (or muscarinic) receptors, located on the involuntary muscle in the walls of the gut. By binding to these receptors dicycloverine prevents certain chemicals produced by the body from interacting with these receptors. This causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm.
Adults : 10 to 20 mg three to four times a day. Maximum recommended oral dose is 160 mg daily in divided dose. Children : Children over 6 months of age- 5 to 10 mg three times a day.
Obstructive uropathy, Obstruction disorder in GIT, Severe ulcerative colitis, Unstable cardiovascular status in acute hemorrhage, Glucoma, Myasthenia gravis, Patients with hypersensitivity to dicycloverine hydrochloride.
Insomnia, headache, weakness, confusion, increased ocular tension, urinary hesitancy, palpitations etc.
Pregnancy Category B. Dicycloverine should be used during pregnancy only if clearly needed. Dicycloverine should not be used in case of lactating mother.
Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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