Desloratadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
H1 -Receptor Antagonist; Antiallergy
Desloratadine, the major active metabolite of Loratadine, is a non-sedating; long acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity. Desloratadine also inhibits histamine release from human mast cell.
ORAL Allergic conditions: Adult: 5 mg once daily. Child: 12 yr: 5 mg once daily; 6-11 yr: 2.5mg; 1-5yr: 1.25 mg;6-11 mth: 1 mg. Doses to be taken once daily.
No clinically relevant drug interactions have been reported.
Hypersensitivity. Severe renal or hepatic failure; child <6 mth, elderly, epilepsy, pregnancy & lactation.
Headache, fatigue, somnolence, dizziness; nausea, dyspepsia; xerostomia, dysmenorrhoea; pharyngitis.
Not recommended during pregnancy. Considering the minimal exposure of a nursing infant to the drugs through breast milk, maternal use of loratadine, desloratadine, or fexofenadine in a standard therapeutic dose is unlikely to result in adverse effects in nursing infants and is considered to be compatible with breastfeeding.
No clinically relevant adverse effects have been reported.
Store in a cool & dry place, protected from light. Store below 30°C. Keep all medicines out of the reach of children.
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