Indicated for the treatment of anxiety & anxiety related disorders like emotional disturbance, functional disturbance in the gastrointestinal system, functional disturbance in the genitourinary system, psychosomatic disorders.
Benzodiazepine; Anxiolytic
Bromazepam is a powerful psychotropic agent. In lower dosage, it selectively reduces tension and anxiety. In higher dosage, it shows sedative and muscle-relaxant properties. Bromazepam binds to the GABA-A receptor producing a conformational change and potentiating its inhibitory effects. Other neurotransmitters are not influenced.
3 mg to 18 mg daily in divided doses.
If bromazepam is combined with other centrally active drugs, its sedative effects may be enhanced. These drugs are antidepressants, hypnotics, narcotics, antipsychotics, sedatives, antiepileptic drugs, sedative antihistamines and anesthetics. Co-administration of cimetidine may prolong the eliminiation half-life of bromazepam. Concomitant intake of bromazepam with alcohol should be avoided, because the sedative effect of bromazepam may be intensified by alcohol.
Patients with known hypersensitivity to benzodiazepines; acute pulmonary insufficiency; respiratory depression; phobic or obsessional states; chronic psychosis. In patients with chronic pulmonary insufficiency, & in patients with chronic renal or hepatic disease, dosage may need to be reduced.
Common adverse Effects include drowsiness, sedation, unsteadiness & ataxia.
Keep in a dry place away from light and heat. Keep out of the reach of children.
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