Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness.
Ethanolamine Derivative; Antihistamine
Diphenhydramine is an antihistamine and works as a topical anti-allergic and analgesic by blocking the releases of histamine at its sources. Zinc is used as a skin protectant.
ORAL Allergic conditions: Adult: As hydrochloride: 25-50 mg 3-4 times daily. Max: 300 mg/day. Child: 6.25-25 mg 3-4 times daily, up to 5 mg/kg in divided doses. Max: 300 mg/day. PARENTERAL Allergic conditions: Adult: As hydrochloride: 10-50mg as a 1% or 5% solution, up to 100 mg. Dose may be given via deep IM or IV inj. Not more than 400 mg in 24 hr. Child: 5 mg/kg daily in 4 divided doses. Dose can be given via deep IM or IV inj. Max: 300 mg in 24 hr.
Hypersensitivity; neonates, lactation. Epilepsy; elderly; performing tasks which require mental alertness; angleclosure glaucoma; pyroduodenal obstruction; urinary tract obstruction; hyperthyroidism; raised intraocular pressure; CV disease; acute asthma; pregnancy.
CNS depression, dizziness, headache, sedation; paradoxical stimulation in children; dryness of mouth, thickened resp secretion, blurring of vision, urinary retention; GI disturbances; blood dyscrasias.
Use is recommended only if clearly needed and the benefit outweighs the risk. Use is not recommended during breastfeeding.
Store below 30°C. Protect from light. Do not freeze.
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