Oxymetazoline nasal spray is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Oxymetazoline nasal spray should not be used to treat children younger than 6 years of age unless it is recommended by a doctor.
Sympathomimetic Agent; Decongestant
Oxymetazoline Hydrochloride is an imidazoline derivative sympathomimetic amine. It is a direct agonist at α-adrenoceptors but has no action on β- adrenoceptors. It is used as a topical agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of the arterioles, thus reducing the blood flow and diminishing swelling of the mucosa. This results in improved potency of the airway and better drainage of the nasal sinus.
NASAL Nasal congestion: Adult: As 0.05% solution: Spray 1-3 times into each nostril bid.Child: 6 yr: Instill or spray 0.05% soln 1-3 times into each nostril bid. OPHTHALMIC Conjunctival decongestant: Adult: l nstil 1-2 drops of 0.025% soln into the eye(s) 6 hrly when necessary. Child: 6 yr: Instill 1-2 drops of 0.025% soln into the eye(s) 6 hrly when necessary.
Oxymetazoline Hydrochloride loride Nasal preparation should not be given to patients being treated with MAO inhibitors or within 14 days of ceasing such treatment.
Glaucoma; hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions. Children <6 yr. Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement; DM.
Nasal drops or spray: Local stinging or burning, sneezing, dryness of mouth & throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye.
Use should be avoided during pregnancy. Use should be avoided during breastfeeding.
Overdose may give rise to local irritation and rebound congestion. Treatment need only be symptomatic.
Keep below 30° C temperature in a dry place, protect from light. Do not refrigerate or freeze. Keep out of the reach of children.
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